Publications

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Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D. ... Feenstra, B. (2022). Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes. Brain : a journal of neurology, 145(2), 555–568. https://doi.org/10.1093/brain/awab260

Demontis, D., Rajagopal, V. M., Thorgeirsson, T. E., Als, T. D., Grove, J., Leppälä, K., Gudbjartsson, D. F., Pallesen, J., Hjorthøj, C., Reginsson, G. W., Tyrfingsson, T., Runarsdottir, V., Qvist, P., Christensen, J. H., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Huckins, L. M., Stahl, E. A., Timmermann, A. ... Børglum, A. D. (2019). Genome-wide association study implicates CHRNA2 in cannabis use disorder. Nature Neuroscience, 22, 1066-1074. https://doi.org/10.1038/s41593-019-0416-1

Anorexia Nervosa Genetics Initiative (2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nature Genetics, 51(8), 1207-1214. https://doi.org/10.1038/s41588-019-0439-2

Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pavlides, J. M. W., Trzaskowski, M., Byrne, E. M., Pers, T. H., Holmans, P. A., Richards, A. L., Abbott, L. ... eQTLGen Consortium (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nature Genetics, 51(5), 793-803. https://doi.org/10.1038/s41588-019-0397-8

Atashi, H., Salavati, M., De Koster, J., Crowe, M., Opsomer, G., GplusE Consortium & Hostens, M. (2020). Genome-wide association for metabolic clusters in early-lactation Holstein dairy cows. Journal of Dairy Science, 103(7), 6392-6406. https://doi.org/10.3168/jds.2019-17369

the iPSYCH-Broad autism group & the 23andMe Research Team (2018). Genome-wide analyses of self-reported empathy: Correlations with autism, schizophrenia, and anorexia nervosa. Translational Psychiatry, 8(1), [35]. https://doi.org/10.1038/s41398-017-0082-6

Tørring, N., Borre, M., Sørensen, K., Andersen, C. L., Wiuf, C. & Ørntoft, T. F. (2007). Genome-Wide analysis of allelic imbalance in laser microdissected prostate cancer tissue using the Affymetrix 50K Mapping array identifies genomic patterns associated with metastasis and differentiation. British Journal of Cancer, 96(3), 499-506. https://doi.org/10.1038/sj.bjc.6603476

Grove, J., Demontis, D., Hollegaard, M. V., Pedersen, C. B., Ørntoft, T. F., Yolken, R., Didriksen, M., Hougaard, D., Wiuf, C. H., Mors, O., Mortensen, P. B. & Børglum, A. (2011). Genome-Wide Significant Interaction by Cytomegalovirus with Respect to Risk of Schizophrenia. Poster session presented at XIX World Congress on Psychiatric Genetics, Washington DC, United States.

Eickhardt, E. A., Als, T. D., Mattheisen, M., Hauberg, M. E., Grove, J., Børglum, A. & Lescai, F. (2015). Genome-Wide Landscape of Genetic Variation with a Functional Impact on Predicted Binding Activity of Transcription Factor Binding Sites. Poster session presented at ESHG 2015, Glasgow, United Kingdom.

Nordentoft, I. K., Birkenkamp-Demtröder, K., Lamy, P., Reinert, T., Vang, S., Hedegaard, J., Thorsen, K., Dyrskjøt, L., Pedersen, J. S. & Ørntoft, T. F. (2014). Genome and RNA sequencing identifies fusion transcripts in bladder cancer. Abstract from AACR Annual Meeting 2014, San Diego, California, United States.

Qian, Y. (2015). Genome Wide Variation Analysis Using High Throughput Data.

Fredsted, T. & Villesen, P. (2005). Genetik og bevaring af truede aber. Aktuel Naturvidenskab, 4, 16-19.

Fredsted, T. & Villesen, P. (2005). Genetik og bevaring af truede aber. Aktuel Naturvidenskab, (4).

Simonsen, V. & Christiansen, F. (1984). Genetics of Zoarces populations XIII. Three loci determining isoenzymes of glutamic-oxaloacetic transaminase. Hereditas, 101, 129–136.

Christiansen, F., Frydenberg, O. & Simonsen, V. (1984). Genetics of Zoarces populations XII. Variations at the polymorphic loci PgmI, PgmII, HbI and EstIII in fjords. Hereditas, 101, 37–48.

Christiansen, F., Nielsen, V. H. & Simonsen, V. (1988). Genetics of Zoarces populations XV: Genetic and morphological variation in Mariager Fjord. Hereditas, 109, 99-112.

Simonsen, V. & Christiansen, F. (1985). Genetics of Zoarces populations XIV. Variation of the lactate dehydrogenase isoenzymes. Hereditas, 103, 177–185.

Simonsen, V. & Christiansen, F. (1981). Genetics of Zoarces populations XI. Inheritance of electrophoretic variants of the enzyme adenosine deaminase. Hereditas, 95, 289-294.

Christiansen, F., Nielsen, B. V. & Simonsen, V. (1981). Genetical and morphological variation in the eelpout Zoarces viviparus. Canadian Journal of Genetics and Cytology, 23, 163-172.

Fredsted, T., Schierup, M. H., Groenevald, L. F. & Kappeler, P. M. (2007). Genetic structure, lack of sex-biased dispersal and behavioral flexibility in the pair-living fat-tailed dwarf lemur, Cheirogaleus medius. Behavioral Ecology and Sociobiology. https://doi.org/10.1007/s00265-006-0323-9

Adams, M. J., Howard, D. M., Luciano, M., Clarke, T-K., Davies, G., Hill, W. D., Smith, D., Deary, I. J., Porteous, D. J., McIntosh, A. M., 23andMe Research Team & Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium (2020). Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition. Psychological Medicine, 50(15), 2526–2535. https://doi.org/10.1017/S0033291719002629

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC , Agrawal, A., Børglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R. ... Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls - CORRIGENDUM. Psychological Medicine, 49(2), 351. https://doi.org/10.1017/S0033291718002945

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Attention Deficit/Hyperactivity Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Autism Spectrum Disorder Working Group of the iPSYCH-Broad-PGC Consortium, Bipolar Disorder Working Group of the PGC, Eating Disorder Working Group of the PGC, Major Depressive Disorder Working Group of the PGC, Obsessive Compulsive Disorders and Tourette Syndrome Working Group of the PGC, Schizophrenia CLOZUK, Substance Use Disorder Working Group of the PGC , Agrawal, A., Borglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H. J., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R. ... Polderman, T. J. C. (2019). Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls. Psychological Medicine, 49(7), 1166-1173. https://doi.org/10.1017/S0033291718002039

Hübel, C., Gaspar, H. A., Coleman, J. R. I., Hanscombe, K. B., Purves, K., Prokopenko, I., Graff, M., Ngwa, J. S., Workalemahu, T., O’Reilly, P. F., Bulik, C. M., Breen, G., ADHD Working Group of the Psychiatric Genomics Consortium, Meta-Analyses of Glucose- and Insulin-related traits Consortium (MAGIC), Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Eating Disorders Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, OCD & Tourette Syndrome Working Group of the Psychiatric Genomics Consortium ... International Headache Genetics Consortium (2019). Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent. Nature Communications, 10(1), [5765]. https://doi.org/10.1038/s41467-019-13544-0

Christiansen, F. (1990). Genetic comparisons of life stages in natural populations of Zoarces viviparus. In J. Adams, A. Hermalin, D. Lam & P. Smouse (Eds.), Convergent Issues in Genetics and Demography (pp. 287-305). Oxford University Press.

Christensen, L. L., Wikman, F., Wiuf, C., Madsen, B. E., Andersen, C. L. & Ørntoft, T. F. (2007). Genetic Variants in MLH1 and MSH2 are not Associated with the Development of Sporadic Colorectal Cancer in Denmark. Poster session presented at The 2nd Biennial Scientific Meeting of the International Society for Gastrointestinal Hereditary Tumours, Yokohama, Japan.

Hernandez-de Sosa, N., Athanasiadis, G., Malouf, J., Laiz, A., Muñoz-Marin, A. M., Herrera, S., Farrerons, J., Soria, J. M. & Casademont, J. (2016). Genetic Contribution of Femoral Neck Bone Geometry to the Risk of Developing Osteoporosis: A Family-Based Study. P L o S One, 11(5), [0154833]. https://doi.org/10.1371/journal.pone.0154833

Feldman, M. W., Otto, S. P. & Christiansen, F. B. (2000). Genes, Culture and Inequality. In K. Arrow, S. Bowles & S. Durlauf (Eds.), Meritocracy and Economic Inequality (pp. 61–85). Princeton University Press.

Mailund, T., Schierup, M. H., Pedersen, C. N. S., Madsen, J. N., Hein, J. & Schauser, L. (2006). GeneRecon—A coalescent based tool for fine-scale association mapping. Bioinformatics, 22(18), 2317–2318.

Mailund, T. (2006). GeneRecon Users' Manual — A coalescent based tool for fine-scale association mapping.

Feldman, M. W., Christiansen, F. B. & Otto, S. P. (2013). Gene-culture co-evolution: teaching, learning, and correlations between relatives. Israel Journal of Ecology & Evolution, 59(2), 72-91. https://doi.org/10.1080/15659801.2013.853435

Hein, J., Schierup, M. H. & Wiuf, C. (2004). Gene genealogies, variation and evolution: A primer in coalescent theory.

Kjeldbjerg, A., Villesen, P., Aagaard, L. & Pedersen, F. S. (2008). Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution. B M C Evolutionary Biology, 8(1), 266. https://doi.org/10.1186/1471-2148-8-266

Maetschke, S. R., Simonsen, M., Davis, M. J. & Mark, A. (2011). Gene Ontology-driven inference of protein-protein interactions using inducers. Bioinformatics, 28(1), 69-75. https://doi.org/10.1093/bioinformatics/btr610

Fredslund, J., Madsen, L. H., Hougaard, B. K., Sandal, N. N., Stougaard, J., Bertioli, D. & Schauser, L. (2006). GeMprospector - online design of cross-species genetic marker candidates in legumes and grasses. Nucleic Acids Research, 34, W670-W675.

Grove, J., Børglum, A. & Pearce, B. D. (2014). GWAS, Cytomegalovirus Infection, and Schizophrenia. Current Behavioral Neuroscience Reports, 1(4), 215-223. https://doi.org/10.1007/s40473-014-0022-1

Swenson, M. S., Anderson, J., Ash, A., Gaurav, P., Sükösd, Z., Bader, D. A., Harvey, S. C. & Heitsch, C. E. (2012). GTfold: Enabling parallel RNA secondary structure prediction on multi-core desktops. BMC Research Notes, 5(341). https://doi.org/10.1186/1756-0500-5-341

Simonsen, M., Thomsen, R., Christensen, M. H. & Pedersen, C. N. S. (2011). GPU-Accelerated High-Accuracy Molecular Docking using Guided Differential Evolution. In GECCO'11 Proceedings of the 13th annual conference on Genetic and evolutionary computation (pp. 1803-1810). Association for Computing Machinery. https://doi.org/10.1145/2001576.2001818

Simonsen, M., Christensen, M. H., Thomsen, R. & Pedersen, C. N. S. (2013). GPU-Accelerated High-Accuracy Molecular Docking using Guided Differential Evolution. In S. tsutsui & P. Collet (Eds.), Massively Parallel Evolutionary Computation on GPGPUs Springer Publishing Company. Natural Computing Series

Lassalle, F., Périan, S., Bataillon, T., Nesme, X., Duret, L. & Daubin, V. (2015). GC-Content evolution in bacterial genomes: the biased gene conversion hypothesis expands. P L o S Genetics, 11(2), e1004941. https://doi.org/10.1371/journal.pgen.1004941

Stukenbrock, E. H., Christiansen, F. B., Hansen, T. T., Dutheil, J. & Schierup, M. H. (2012). Fusion of two divergent fungal individuals led to the recent emergence of a unique widespread pathogen species. Proceedings of the National Academy of Sciences of the United States of America, 107(27). https://doi.org/10.1073/pnas.1201403109

Sørensen, J. L., Knudsen, M., Hansen, F. T., Olesen, C., Romans Fuertes, P., Lee, T. V., Søndergaard, T. E., Pedersen, C. N. S., Brodersen, D. E. & Giese, H. (2014). Fungal NRPS-dependent siderophores: From function to prediction. In J-F. Martin, C. Garcia-Estrada & S. Zeilinger (Eds.), Biosynthesis and Molecular Genetics of Fungal Secondary Metabolites (pp. 317-339). Springer. Fungal Biology https://doi.org/10.1007/978-1-4939-1191-2_15

Mailund, T. (2017). Functional data structures in R: advanced statistical programming in R. Apress. http://link.springer.com/10.1007/978-1-4842-3144-9

Mailund, T. (2017). Functional Programming in R: Advanced Statistical Programming for Data Science, Analysis and Finance . Apress.

Sukosd, Z., Andersen, E. S., Seemann, S. E., Jensen, M., Hansen, M. B., Gorodkin, J. & Kjems, J. (2015). Full-length RNA structure prediction of the HIV-1 genome reveals a conserved core domain. Nucleic Acids Research, 43(21), 10168-10179. https://doi.org/10.1093/nar/gkv1039

Bataillon, T., Gauthier, P., Villesen, P., Santoni, S., Thompson, J. D. & Ehlers, B. (2022). From genotype to phenotype: Genetic redundancy and the maintenance of an adaptive polymorphism in the context of high gene flow. Evolution Letters, 6(2), 189-202. https://doi.org/10.1002/evl3.277

Ratmann, O., Wiuf, C. H. & Pinney, J. W. (2009). From evidence to inference: probing the evolution of protein interaction networks. H F S P Journal, 3(5), 290-306. https://doi.org/10.2976/1.3167215

Andersen, C. L., Wiuf, C., Kruhøffer, M., Korsgaard, M., Laurberg, S. & Ørntoft, T. F. (2007). Frequent occurrence of uniparental disomy in colorectal cancer. Carcinogenesis, 28(1), 38-48. https://doi.org/10.1093/carcin/bgl086

Andersen, C. L., Lamy, P., Thorsen, K., Kjeldsen, E., Wikman, F., Villesen, P., Øster, B., Laurberg, S. & Ørntoft, T. F. (2010). Frequent genomic loss at chr16p13.2 is associated with poor prognosis in colorectal cancer. International Journal of Cancer. https://doi.org/10.1002/ijc.25841

Christiansen, F. (1988). Frequency-dependence and competition. Royal Society of London. Philosophical Transactions. Biological Sciences, 319, 587-600.

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Palle Villesen