Lassen, J., Nielsen, K. L., Johannsen, M. & Villesen, P. (2021). Assessment of XCMS Optimization Methods with Machine-Learning Performance. Analytical Chemistry, 93(40), 13459-13466. https://doi.org/10.1021/acs.analchem.1c02000

Wathes, D. C., Becker, F., Buggiotti, L., Crowe, M. A., Ferris, C. P., Foldager, L., Grelet, C., Hostens, M., Ingvartsen, K. L., Marchitelli, C., Salavati, M., Signorelli, F., Takeda, H., Tang, L., Cheng, Z. & GplusE Consortium (2021). Associations between circulating IGF-1 concentrations, disease status and the leukocyte transcriptome in early lactation dairy cows. Ruminants, 1(2), 147-177. https://doi.org/10.3390/ruminants1020012

Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasés, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M., Mors, O., Mortensen, P. B., ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Cormand, B., Hougaard, D. M., Neale, B. M., Franke, B. ... Børglum, A. D. (2021). Author Correction: Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder (Nature communications (2021) 12 1 (576)). Nature Communications, 12, Article 1166. https://doi.org/10.1038/s41467-021-21566-w

Jefsen, O. H., Speed, M., Speed, D. & Østergaard, S. D. (2021). Bipolar disorder and cannabis use: A bidirectional two-sample Mendelian randomization study. Addiction Biology, 26(6), Article 13030. https://doi.org/10.1111/adb.13030

van der Zalm, Y. C., Foldager, L., Termorshuizen, F., Sommer, I. E., Nielsen, J. & Selten, J.-P. (2021). Clozapine and mortality: A comparison with other antipsychotics in a nationwide Danish cohort study. Acta Psychiatrica Scandinavica, 143(3), 216-226. https://doi.org/10.1111/acps.13267

Buggiotti, L., Cheng, Z., Salavati, M., Wathes, D. C. & GplusE Consortium (2021). Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes. BMC Genomics, 22(1), 1-17. Article 693. https://doi.org/10.1186/s12864-021-07977-5

Munch, T. N., Hedley, P. L., Hagen, C. M., Bækvad-Hansen, M., Bybjerg-Grauholm, J., Grove, J., Nordentoft, M., Børglum, A. D., Mortensen, P. B., Werge, T. M., Melbye, M., Hougaard, D. M. & Christiansen, M. (2021). Co-occurring hydrocephalus in autism spectrum disorder: a Danish population-based cohort study. Journal of Neurodevelopmental Disorders, 13(1), 19. Article 19. https://doi.org/10.1186/s11689-021-09367-0

Wathes, D. C., Cheng, Z., Salavati, M., Buggiotti, L., Takeda, H., Tang, L., Becker, F., Ferris, C. P., Hostens, M., Crowe, M. A. & GplusE Consortium (2021). Corrigendum to "Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation" (J. Dairy Sci. 104: 3596-3616). Journal of Dairy Science, 104(5), 6327. https://doi.org/10.3168/jds.2021-104-5-6327

Coll Macià, M., Skov, L., Peter, B. M. & Schierup, M. H. (2021). Different historical generation intervals in human populations inferred from Neanderthal fragment lengths and mutation signatures. Nature Communications, 12(1), Article 5317. https://doi.org/10.1038/s41467-021-25524-4

Muyle, A., Martin, H., Zemp, N., Mollion, M., Gallina, S., Tavares, R., Silva, A., Bataillon, T., Widmer, A., Glémin, S., Touzet, P. & Marais, G. A. B. (2021). Dioecy Is Associated with High Genetic Diversity and Adaptation Rates in the Plant Genus Silene. Molecular Biology and Evolution, 38(3), 805-818. https://doi.org/10.1093/molbev/msaa229

Verhoef, E., Grove, J., Shapland, C. Y., Demontis, D., Burgess, S., Rai, D., Børglum, A. D. & St Pourcain, B. (2021). Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy. Nature Communications, 12, Article 6534. https://doi.org/10.1038/s41467-021-26755-1

Starnawska, A., Bukowski, L., Chernomorchenko, A., Elfving, B., Müller, H. K., van den Oord, E., Aberg, K., Guintivano, J., Grove, J., Mors, O., Børglum, A. D., Nielsen, A. L., Qvist, P. & Staunstrup, N. H. (2021). DNA methylation of the KLK8 gene in depression symptomatology. Clinical Epigenetics, 13(1), Article 200. https://doi.org/10.1186/s13148-021-01184-5

Larsen, M., Amorim Franchi, G., Herskin, M. S., Foldager, L., Larsen, M. L. V., Hernandez Castellano, L. E., Sørensen, M. T. & Jensen, M. B. (2021). Effects of feeding level, milking frequency, and single injection of cabergoline on feed intake, milk yield, milk leakage, and clinical udder characteristics during dry-off in dairy cows. Journal of Dairy Science, 104(10), 11108-11125. Article 20289. https://doi.org/10.3168/jds.2021-20289

Jessen, C. T., Foldager, L. & Riber, A. B. (2021). Effects of hatching on-farm on behaviour, first week performance, fear level and range use of organic broilers. Applied Animal Behaviour Science, 238, Article 105319. https://doi.org/10.1016/j.applanim.2021.105319

Jessen, C. T., Foldager, L. & Riber, A. B. (2021). Effects of hatching on-farm on performance and welfare of organic broilers. Poultry Science, 100(9), Article 101292. https://doi.org/10.1016/j.psj.2021.101292

Chen, Y., Vanderick, S., Mota, R. R., Grelet, C., GplusE Consortium & Gengler, N. (2021). Estimation of genetic parameters for predicted nitrogen use efficiency and losses in early lactation of Holstein cows. Journal of Dairy Science, 104(4), 4413-4423. https://doi.org/10.3168/jds.2020-18849

Soraggi, S., Riera Belles, M., Rajpert-De Meyts, E., Schierup, M. H. & Almstrup, K. (2021). Evaluating genetic causes of azoospermia: What can we learn from a complex cellular structure and single-cell transcriptomics of the human testis? Human Genetics, 140(1), 183-201. https://doi.org/10.1007/s00439-020-02116-8

Yang, C., Zhou, Y., Marcus, S., Formenti, G., Bergeron, L. A., Song, Z., Bi, X., Bergman, J., Rousselle, M. M. C., Zhou, C., Zhou, L., Deng, Y., Fang, M., Xie, D., Zhu, Y., Tan, S., Mountcastle, J., Haase, B., Balacco, J. ... Zhang, G. (2021). Evolutionary and biomedical insights from a marmoset diploid genome assembly. Nature, 594(7862), 227-233. https://doi.org/10.1038/s41586-021-03535-x

Privé, F., Zhu, Z. & Vilhjalmsson, B. J. (2021). Finding hidden treasures in summary statistics from genome-wide association studies. Nature Genetics, 53(4), 431-432. https://doi.org/10.1038/s41588-021-00824-z

Mullins, N., Forstner, A. J., O'Connell, K. S., Coombes, B., Coleman, J. R. I., Qiao, Z., Als, T. D., Bigdeli, T. B., Børte, S., Bryois, J., Charney, A. W., Drange, O. K., Gandal, M. J., Hagenaars, S. P., Ikeda, M., Kamitaki, N., Kim, M., Krebs, K., Panagiotaropoulou, G. ... HUNT All-In Psychiatry (2021). Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nature Genetics, 53(6), 817-829. https://doi.org/10.1038/s41588-021-00857-4

Ernst, M., Rogers, S., Lausten-Thomsen, U., Bjorkbom, A., Laursen, S. S., Courraud, J., Borglum, A., Nordentoft, M., Werge, T., Mortensen, P. B., Hougaard, D. M. & Cohen, A. S. (2021). Gestational age-dependent development of the neonatal metabolome. Pediatric Research, 89(6), 1396-1404. https://doi.org/10.1038/s41390-020-01149-z

Cheng, Z., Buggiotti, L., Salavati, M., Marchitelli, C., Palma-Vera, S., Wylie, A., Takeda, H., Tang, L., Crowe, M. A., Wathes, D. C. & GplusE Consortium (2021). Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis. Molecular Biology Reports, 48, 4611-4623. https://doi.org/10.1007/s11033-021-06494-8

Thomsen, A. H., Leth, P. M., Hougen, H. P. & Villesen, P. (2021). Gunshot homicides in Denmark 1992-2016. International Journal of Legal Medicine (Online), 135(4), 1507-1514. https://doi.org/10.1007/s00414-021-02548-5

Jørgensen, C. S., Horsdal, H. T., Rajagopal, V. M., Grove, J., Als, T. D., Kamperis, K., Nyegaard, M., Walters, G. B., Eðvarðsson, V. Ö., Stefánsson, H., Nordentoft, M., Hougaard, D. M., Werge, T., Mors, O., Mortensen, P. B., Agerbo, E., Rittig, S., Stefánsson, K., Børglum, A. D. ... Christensen, J. H. (2021). Identification of genetic loci associated with nocturnal enuresis: a genome-wide association study. The Lancet Child and Adolescent Health, 5(3), 201-209. https://doi.org/10.1016/S2352-4642(20)30350-3

Foldager, L., Winters, J., Nørskov, N. & Sørensen, M. T. (2021). Impact of feed glyphosate residues on broiler breeder egg production and egg hatchability. Scientific Reports, 11, Article 19290. https://doi.org/10.1038/s41598-021-98962-1

Zhang, Q., Privé, F., Vilhjálmsson, B. & Speed, D. (2021). Improved genetic prediction of complex traits from individual-level data or summary statistics. Nature Communications, 12(1), Article 4192. https://doi.org/10.1038/s41467-021-24485-y

Wright, M., Smed, M. K., Nelson, J. L., Olsen, J., Hetland, M. L., Zoffmann, V. & Jawaheer, D. (2021). Is gene expression among women with rheumatoid arthritis dysregulated during a postpartum flare? Arthritis Research and Therapy, 23, Article 30. https://doi.org/10.1186/s13075-021-02418-w

Leroy, T., Rousselle, M., Tilak, M. K., Caizergues, A. E., Scornavacca, C., Recuerda, M., Fuchs, J., Illera, J. C., De Swardt, D. H., Blanco, G., Thébaud, C., Milá, B. & Nabholz, B. (2021). Island songbirds as windows into evolution in small populations. Current Biology, 31(6), 1303-1310.e4. https://doi.org/10.1016/j.cub.2020.12.040

Albiñana, C., Grove, J., McGrath, J. J., Agerbo, E., Wray, N. R., Bulik, C. M., Nordentoft, M., Hougaard, D. M., Werge, T., Børglum, A. D., Mortensen, P. B., Privé, F. & Vilhjálmsson, B. J. (2021). Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction. American Journal of Human Genetics, 108(6), 1001-1011. https://doi.org/10.1016/j.ajhg.2021.04.014

Nielsen, M. M. & Pedersen, J. S. (2021). miRNA activity inferred from single cell mRNA expression. Scientific Reports, 11(1), Article 9170. https://doi.org/10.1038/s41598-021-88480-5

Julienne, H., Laville, V., McCaw, Z. R., He, Z., Guillemot, V., Lasry, C., Ziyatdinov, A., Nerin, C., Vaysse, A., Lechat, P., Ménager, H., Le Goff, W., Dube, M.-P., Kraft, P., Ionita-Laza, I., Vilhjálmsson, B. J. & Aschard, H. (2021). Multitrait GWAS to connect disease variants and biological mechanisms. PLOS Genetics, 17(8), Article e1009713. https://doi.org/10.1371/journal.pgen.1009713

Dominguez-Valentin, M., Plazzer, J. P., Sampson, J. R., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Macrae, F., Winship, I. M., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., de Vos tot Nederveen Cappel, W. H., Sijmons, R. H., Nielsen, M. ... Møller, P. (2021). No difference in penetrance between truncating and missense/aberrant splicing pathogenic variants in mlh1 and msh2: A prospective lynch syndrome database study. Journal of Clinical Medicine, 10(13), Article 2856. https://doi.org/10.3390/jcm10132856

Ehlers, B., Bataillon, T. & Damgaard, C. (2021). Ongoing decline in insect-pollinated plants across Danish grasslands. Biology Letters, 17(11), Article 0210493. https://doi.org/0.1098/rsbl.2021.0493

Krogh, U., Højberg, O., Foldager, L., Rani, S., Nørskov, N. P. & Sørensen, M. T. (2021). Performance and mineral status of weaning pigs fed diets with different levels of glyphosate and tryptophan. Livestock Science, 252, Article 104681. https://doi.org/10.1016/j.livsci.2021.104681

Riber, A. B., Herskin, M. S., Foldager, L., Sandercock, D. A., Murrell, J. & Tahamtani, F. (2021). Post-mortem examination of fast-growing broilers with different degrees of identifiable gait defects. Veterinary Record, 189(7), Article e454. https://doi.org/10.1002/vetr.454

Kjældgaard, A. L., Pilely, K., Olsen, K. S., Jessen, A. H., Lauritsen, A. Ø., Pedersen, S. W., Svenstrup, K., Karlsborg, M., Thagesen, H., Blaabjerg, M., Theódórsdóttir, Á., Elmo, E. G., Møller, A. T., Bonefeld, L., Berg, M., Garred, P. & Møller, K. (2021). Prediction of survival in amyotrophic lateral sclerosis: a nationwide, Danish cohort study. BMC Neurology, 21(1), Article 164. https://doi.org/10.1186/s12883-021-02187-8

Draghi, A., Chamberlain, C. A., Khan, S., Papp, K., Lauss, M., Soraggi, S., Radic, H. D., Presti, M., Harbst, K., Gokuldass, A., Kverneland, A., Nielsen, M., Westergaard, M. C. W., Andersen, M. H., Csabai, I., Jönsson, G., Szallasi, Z., Svane, I. M. & Donia, M. (2021). Rapid Identification of the Tumor-Specific Reactive TIL Repertoire via Combined Detection of CD137, TNF, and IFNγ, Following Recognition of Autologous Tumor-Antigens. Frontiers in Immunology, 12, Article 705422. https://doi.org/10.3389/fimmu.2021.705422

Cavassim, M. I. A., Andersen, S. U., Bataillon, T. & Schierup, M. H. (2021). Recombination facilitates adaptive evolution in rhizobial soil bacteria. Molecular Biology and Evolution, 38(12), 5480-5490. https://doi.org/10.1093/molbev/msab247

Norager, N. H., Olsen, M. H., Pedersen, S. H., Riedel, C. S., Czosnyka, M. & Juhler, M. (2021). Reference values for intracranial pressure and lumbar cerebrospinal fluid pressure: a systematic review. Fluids and Barriers of the CNS, 18(1), Article 19. https://doi.org/10.1186/s12987-021-00253-4

Wathes, D. C., Cheng, Z., Salavati, M., Buggiotti, L., Takeda, H., Tang, L., Becker, F., Ingvartsen, K. L., Ferris, C. P., Hostens, M., Crowe, M. A. & GplusE Consortium (2021). Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation. Journal of Dairy Science, 104(3), 3596-3616. https://doi.org/10.3168/jds.2020-19165

Agerbo, E., Trabjerg, B. B., Børglum, A. D., Schork, A. J., Vilhjálmsson, B. J., Pedersen, C. B., Hakulinen, C., Albiñana, C., Hougaard, D. M., Grove, J., McGrath, J. J., Bybjerg-Grauholm, J., Mors, O., Plana-Ripoll, O., Werge, T., Wray, N. R., Mortensen, P. B. & Musliner, K. L. (2021). Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status. JAMA Psychiatry, 78(4), 387-397. https://doi.org/10.1001/jamapsychiatry.2020.4172

Demontis, D., Walters, R. K., Rajagopal, V. M., Waldman, I. D., Grove, J., Als, T. D., Dalsgaard, S., Ribasas, M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Werge, T., Nordentoft, M., Mors, O., Mortensen, P. B., ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Cormand, B., Hougaard, D. M., Neale, B. M., Franke, B. ... Børglum, A. D. (2021). Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder. Nature Communications, 12(1), Article 576. https://doi.org/10.1038/s41467-020-20443-2

Munn-Chernoff, M. A., Johnson, E. C., Chou, Y.-L., Coleman, J. R. I., Thornton, L. M., Walters, R. K., Yilmaz, Z., Baker, J. H., Hübel, C., Gordon, S., Medland, S. E., Watson, H. J., Gaspar, H. A., Bryois, J., Hinney, A., Leppä, V. M., Mattheisen, M., Ripke, S., Yao, S. ... Agrawal, A. (2021). Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies. Addiction Biology, 26(1), Article e12880. https://doi.org/10.1111/adb.12880

De, T., Goncalves, A., Speed, D., Froguel, P., NFBC consortium, Gaffney, D. J., Johnson, M. R., Jarvelin, M.-R. & Coin, L. J. (2021). Signatures of TSPAN8 variants associated with human metabolic regulation and diseases. iScience, 24(8), Article 102893. https://doi.org/10.1016/j.isci.2021.102893

Mørup, N., Stakaitis, R., Golubickaite, I., Riera, M., Dalgaard, M. D., Schierup, M. H., Jørgensen, N., Daugaard, G., Juul, A. & Almstrup, K. (2021). Small RNAs in Seminal Plasma as Novel Biomarkers for Germ Cell Tumors. Cancers, 13(10), Article 2346. https://doi.org/10.3390/cancers13102346

Maag, E., Kulasingam, A., Grove, E. L., Pedersen, K. S., Kristensen, S. D. & Hvas, A. M. (2021). Statistical and machine learning methods for analysis of multiplex protein data from a novel proximity extension assay in patients with ST-elevation myocardial infarction. Scientific Reports, 11(1), Article 13787. https://doi.org/10.1038/s41598-021-93162-3

Capion, N., Raundal, P., Foldager, L. & Thomsen, P. T. (2021). Status of claw recordings and claw health in Danish dairy cattle from 2013 to 2017. The Veterinary Journal, 277, Article 105749. https://doi.org/10.1016/j.tvjl.2021.105749

Bergeron, L. A., Besenbacher, S., Schierup, M. H. & Zhang, G. (2021). Studying mutation rate evolution in primates-a need for systematic comparison of computational pipelines. GigaScience, 10(10), Article giab072. https://doi.org/10.1093/gigascience/giab072