Section for Bioinformatics and Computational Biology

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 BiRC Research Publications

Publications

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Hobolth, A. & Stone, E. (2009). Simulation from endpoint-conditioned, continuous-time Markov chains on a finite state space, with applications to molecular evolution. Annals of Applied Statistics, 3(3), 1204-1231. https://doi.org/10.1214/09-AOAS247
Wiuf, C. H. & Andersen, C. L. (Eds.) (2009). Statistics and Informatics in Molecular Cancer Research. (1 ed.) Oxford University Press.
Wiuf, C. H. & Andersen, C. L. (Eds.) (2009). Statistics and Informatics in Molecular Cancer Research. Oxford University Press.
Andersen, L. N. & Mandjes, M. (2009). Structural properties of reflected Lévy processes. Queueing Systems, 63(1-4), 301-322. https://doi.org/10.1007/s11134-009-9116-y
Pradal, C., Olesen, J. M. & Wiuf, C. H. (2009). Temporal development and collapse of an Arctic plant-pollinator network. BMC Ecology, 9. https://doi.org/10.1186/1472-6785-9-24
Liljas, A., Liljas, L., Piskur, J., Lindblom, G., Nissen, P. & Kjeldgaard, M. (2009). Textbook on Structural Biology. (1 ed.) World Scientific.
Hobolth, A. & Wiuf, C. H. (2009). The genealogy, site frequency spectrum and ages of two nested mutant alleles. Theoretical Population Biology, 75(4), 260-265. https://doi.org/10.1016/j.tpb.2009.02.001
Schoustra, S. E., Bataillon, T., Gifford, D. R. & Kassen, R. (2009). The properties of adaptive walks in evolving populations of fungus. PLoS Biology, 7(11), e1000250. https://doi.org/10.1371/journal.pbio.1000250
Emily, M., Mailund, T., Hein, J., Schauser, L. & Schierup, M. H. (2009). Using biological networks to search for interacting loci in genomewide association studies. European Journal of Human Genetics. https://doi.org/10.1038/ejhg.2009.15
Djernes, J. K., Gulmann, N. C., Ibsen, M., Foldager, L., Olesen, F. & Munk-Jørgensen, P. (2008). A follow-up of elderly depressed patients. Nordic Journal of Psychiatry, 62(3), 233-41. https://doi.org/10.1080/08039480802088296
Kristensen, T. G. & Pedersen, C. S. (2008). All-to-all RF Distance Methods. Poster session presented at Bioinformatics 2008, Warszawa, Poland.
Knudsen, M. & Wiuf, C. (2008). A Markov chain approach to Randomly Grown Graphs. Journal of Applied Mathematics. https://doi.org/10.1155/2008/190836
Hobolth, A. (2008). A Markov chain Monte Carlo Expectation Maximization Algorithm for Statistical Analysis of DNA Sequence Evolution with Neighbor-Dependent Substitution Rates. Journal of Computational and Graphical Statistics, 17(1), 138-162.
Knudsen, M., Penner, R., Andersen, J. E. & Wiuf, C. H. (2008). An Algebraic Topology Approach to the Classification of Protein Domain Structures. Poster session presented at 6th Annual Rocky Mountain Bioinformatics Conference, Snowmass Village, Colorado, United States.
Wiuf, C., Ratmann, O. & Knudsen, M. (2008). Analysis of biological network data using likelihood-free inference techniques. In M. Ahdesmäki, K. Strimmer, N. Radde, J. Rahnenführer, K. Klemm, H. Lähdesmäki & O. Yli-Harja (Eds.), Ikke angivet (pp. 185-188). <Forlag uden navn>.
Herbsleb, M., Christensen, O. F., Thykjaer, T., Wiuf, C., Borre, M., Ørntoft, T. F. & Dyrskjøt, L. (2008). Bioinformatic identification of FGF, p38-MAPK, and calcium signalling pathways associated with carcinoma in situ in the urinary bladder. B M C Cancer, 8, 37. https://doi.org/10.1186/1471-2407-8-37
Besenbacher, S. (2008). Challenges in whole-genome association mapping.
d'Amore, F., Chan, E., Iqbal, J., Geng, H., Young, K., Xiao, L., Hess, M. M., Sanger, W. G., Smith, L., Wiuf, C., Hagberg, O., Fu, K., Chan, W. C. & Dave, B. J. (2008). Clonal evolution in t(14;18)-positive follicular lymphoma, evidence for multiple common pathways, and frequent parallel clonal evolution. Clinical Cancer Research, 14(22), 7180-7. https://doi.org/10.1158/1078-0432.CCR-08-0752
Stissing, M., Mailund, T., Pedersen, C. S., Brodal, G. S. & Fagerberg, R. (2008). Computing the all-pairs quartet distance on a set of evolutionary trees. Journal of Bioinformatics and Computational Biology, 6(1), 37-50.
Johnson, S. S., Hebsgaard, M. B., Christensen, T. R., Mastepanov, M., Nielsen, R., Munch, K., Brand, T., Gilbert, M. T. P., Zuber, M. T., Bunce, M., Rønn, R., Gilichinsky, D., Froese, D. & Willerslev, E. (2008). Correction for Johnson et al., Ancient bacteria show evidence of DNA repair. Proceedings of the National Academy of Sciences (PNAS), 105(30). https://doi.org/10.1073/pnas.0804198105
Fredslund, J. (2008). DATFAP: A Database of Primers and Homology Alignments for Transcription Factors from 13 Plant Species. BMC Genomics.
Dutheil, J. (2008). Detecting site-specific biochemical constraints through substitution mapping. Journal of Molecular Evolution, 67(3), 257-65. https://doi.org/10.1007/s00239-008-9139-8
Schiøtt, B. & Lie, M. A. (2008). DFT Study of Solvation Effects on the Tautomeric Equlibrium and Catalytic Ylide Generation of Thiamin Models. Journal of Computational Chemistry, 29, 1037-1047.
Schepeler, T., Reinert, T., Ostenfeld, M. S., Christensen, L. L., Silahtaroglu, A. N., Dyrskjøt, L., Wiuf, C., Sørensen, F. J., Kruhøffer, M., Laurberg, S., Kauppinen, S., Ørntoft, T. F. & Andersen, C. L. (2008). Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Research, 68(15), 6416-24. https://doi.org/10.1158/0008-5472.CAN-07-6110
Ding, Z., Mailund, T. & Song, Y. (2008). Efficient Whole-Genome Association Mapping using Local Phylogenies for Unphased Genome Data. Bioinformatics, 2215-2221.
Stumpf, M. PH., Thorne, T., Silva, E., Stewart, R., An, HJ., Lappe, M. & Wiuf, C. H. (2008). Estimating the size of the human interactome. Proceedings of the National Academy of Sciences (PNAS), 105, 6059.
Christiansen, F. B. (2008). Evolutionær tilpasning. Matilde, (38), 16-19.
Penn, O., Stern, A., Rubinstein, N. D., Dutheil, J., Bacharach, E., Galtier, N. & Pupko, T. (2008). Evolutionary modeling of rate shifts reveals specificity determinants in HIV-1 subtypes. PLoS Computational Biology, 4(11), e1000214. https://doi.org/10.1371/journal.pcbi.1000214
Kjeldbjerg, A., Villesen, P., Aagaard, L. & Pedersen, F. S. (2008). Gene conversion and purifying selection of a placenta-specific ERV-V envelope gene during simian evolution. BMC Evolutionary Biology, 8(1), 266. https://doi.org/10.1186/1471-2148-8-266
Schierup, M. H. & Vekemans, X. (2008). Genomic consequences of selection on self-incompatibility genes. Current Opinion in Plant Biology, 116-122. https://doi.org/10.1016/j.pbi.2008.01.003
Madsen, B. E., Ramos, E. M., Boulard, M., Duda, K., Overgaard, J., Nordsmark, M., Wiuf, C. & Hansen, L. L. (2008). Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer. PLoS One, 3(6), e2492. https://doi.org/10.1371/journal.pone.0002492
Hobolth, A., Uyenoyama, M. K. & Wiuf, C. (2008). Importance sampling for the infinite sites model. Statistical Applications in Genetics and Molecular Biology, 7(1). https://doi.org/10.2202/1544-6115.1400
Herbsleb, M., Birkenkamp-Demtröder, K., Andersen, T. T., Wiuf, C., Hein, A.-M. K., Ørntoft, T. F. & Andersen, L. D. (2008). Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells. BMC Medical Genomics, 1. https://doi.org/10.1186/1755-8794-1-31
Herbsleb, M., Birkenkamp-Demtroder, K., Thykjaer, T., Wiuf, C., Hein, A.-M. K., Orntoft, T. F. & Andersen, L. D. (2008). Increased cell motility and invasion upon knockdown of lipolysis stimulated lipoprotein receptor (LSR) in SW780 bladder cancer cells. BMC Medical Genomics, 1, 31. https://doi.org/10.1186/1755-8794-1-31
de Groot, S., Mailund, T., Lunter, G. & Hein, J. (2008). Investigating Selection on Viruses: A Statistical Alignment Approach. BMC Bioinformatics, 9(308).
Christiansen, F. (2008). Leder. Matilde, (34), 2.
Hougaard, B. K., Madsen, L. H., Sandal, N., de Carvalho Moretzsohn, M., Fredslund, J., Schauser, L., Nielsen, A. M., Rohde, T., Sato, S., Tabata, S., Bertioli, D. J. & Stougaard, J. (2008). Legume anchor markers link syntenic regions between Phaseolus vulgaris, Lotus japonicus, Medicago truncatula and Arachis. Genetics, 179(4), 2299-312. https://doi.org/10.1534/genetics.108.090084
Besenbacher, S., Mailund, T. & Schierup, M. H. (2008). Local Phylogeny Mapping of Quantitative Traits: Higher Accuracy and Better Ranking Than Single Marker Association in Genomewide Scans. Genetics. https://doi.org/10.1534/genetics.108.092643
Musgaard, M., Thøgersen, L. & Schiøtt, H. B. (2008). Molecular Dynamics Simulations of the E2 Form of the Ca2+-ATPase: Preliminary Results. Poster session presented at 12th International ATPase Conference. Na,K-ATPase and Related Transport ATPases of P-type: Structures, Mechanisms, and Roles in Health and Disease, Aarhus, Denmark.
Dutheil, J. & Boussau, B. (2008). Non-homogeneous models of sequence evolution in the Bio++ suite of libraries and programs. BMC Evolutionary Biology, 8, 255. https://doi.org/10.1186/1471-2148-8-255
Li, J., Gromov, P., Gromova, I., Moreira, J. M., Timmermans-Wielenga, V., Rank, F., Wang, K., Li, S., Li, H., Wiuf, C., Yang, H., Zhang, X., Bolund, L. & Celis, J. E. (2008). Omics-based profiling of carcinoma of the breast and matched regional lymph node metastasis. Proteomics, 8(23-24), 5038-52. https://doi.org/10.1002/pmic.200800303
Andersen, L. N. & Asmussen, S. (2008). Parallel computing, failure recovery and extreme values. Journal of Statistical Theory and Practice, 2(2), 279-292.
Thøgersen, L., Schiøtt, B., Vosegaard, T., Nielsen, N. C. & Tajkhorshid, E. (2008). Peptide Aggregation and Pore Formation in a Lipid Bilayer: A Combined Coarse-Grained and All Atom Molecular Dynamics Study. Biophysical Journal, 95(9), 4337-4347. https://doi.org/10.1529/biophysj.108.133330
Simonsen, M., Mailund, T. & Pedersen, C. S. (2008). Rapid Neighbour-Joining. In Proceedings of the 8th International Workshop on Algorithms in Bioinformatics (WABI) (pp. 113-122)
Castric, V., Bechsgaard, J., Schierup, M. H. & Vekemans, X. (2008). Repeated adaptive introgression at a gene under multiallelic balancing selection. PLoS Genetics, 4(8), e1000168. https://doi.org/10.1371/journal.pgen.1000168
Vosegaard, T., Bertelsen, K., Pedersen, J. M., Thøgersen, L., Schiøtt, B., Tajkhorshid, E., Skrydstrup, T. & Nielsen, N. C. (2008). Resolution Enhancement in Solid-State NMR of Oriented Membrane Proteins by Anisotropic Differential Linebroadening. Journal of the American Chemical Society, 130, 5028-5029.
Preker, P., Nielsen, J., Kammler, S., Lykke-Andersen, S., Christensen, M. S., Mapendano, C. K., Schierup, M. H. & Jensen, T. H. (2008). RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters. Science, 322(5909), 1851-1854. https://doi.org/10.1126/science.1164096
Foldager, L., Steffensen, R. N., Thiel, S., Als, T. D., Kristensen, A. S., Straarup, S., Nielsen, H. J., Nordentoft, M., Mortensen, P. B., Rosenberg, R., Mors, O. & Jensenius, J. C. (2008). Schizophrenia and innate immune defense: association study of mannan-bindinglectin (MBL) and MBL-associated serine proteases-2 (MASP-2) deficiency. In WCPG 2008 Abstract Book (pp. 225)
Schierup, M. H., Bechsgaard, J. S. & Christiansen, F. B. (2008). Selection at work in self-incompatible Arabidopsis lyrata. II. Spatial distribution of S haplotypes in Iceland. Genetics, 180(2), 1051-9. https://doi.org/10.1534/genetics.108.088799
Jakobsen, H. J., Brorson, M., Bildsøe, H. K., Skibsted, J. & Hansen, M. R. (2008). Sensitivity Enhancement in Natural Abundance Solid-State 33S MAS NMR Spectroscopy Employing Adiabatic Inversion Pulses to the Satellite Transitions. Abstract from 49th Experimental NMR Conference, Asilomar, Pacific Grove, California, United States.

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Palle Villesen