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Unprecedented exploration generates most comprehensive map of cancer genomes charted to date

Pan-Cancer Project discovers causes of previously unexplained cancers, pinpoints cancer-causing events and zeroes in on mechanisms of development.

2020.02.06 | Ellen Bernadette Noer

PCAWG cover tumour landscape

 

 

 

 

An international team has completed the most comprehensive study of whole cancer genomes to date, significantly improving our fundamental understanding of cancer and signposting new directions for its diagnosis and treatment.

 

 

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Project (PCAWG), known as the Pan-Cancer Project), a collaboration involving more than 1,300 scientists and clinicians from 37 countries, analyzed more than 2,600 genomes of 38 different tumour types, creating a huge resource of primary cancer genomes. This was then the launch-point for 16 working groups studying multiple aspects of cancer’s development, causation, progression and classification. 

Read the press release 'Unprecedented exploration generates most comprehensive map of cancer genomes charted to date' here.

Read the Danish Press release 'Globalt studie kortlægger kræftmutationer i stort katalog' here.

Read the special edition of Nature, in which most of the PCAWG consortium's results are collected and published, here.

Read the article 'Analyses of non-coding somatic drivers in 2,658 cancer whole genomes' here.

Read more about the PCAWG Consortium here.

 

 

 

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