Publications

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Qian, Y., Besenbacher, S., Mailund, T. & Schierup, M. H. (2014). Identifying disease associated genes by network propagation. B M C Systems Biology, 8(Suppl 1), S6. https://doi.org/10.1186/1752-0509-8-S1-S6

Mailund, T., Munch, K. & Schierup, M. H. (2014). Inferring the Process of Human–Chimpanzee Speciation. In Encyclopedia of Life Sciences Wiley. https://doi.org/10.1002/9780470015902.a0020833.pub2

GROUP Investigators & iPSYCH-GEMS SCZ (Jakob Grove, member of -) (2014). Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia. P L o S Genetics, 10(6), e1004345. https://doi.org/10.1371/journal.pgen.1004345

Pedersen, B. P., Ifrim, G., Liboriussen, P., Axelsen, K. B., Palmgren, M. G., Nissen, P., Wiuf, C. H. & Pedersen, C. N. S. (2014). Large Scale Identification and Categorization of Protein Sequences Using Structured Logistic Regression. P L o S One, 9(1), Article e85139. https://doi.org/10.1371/journal.pone.0085139

Mailund, T., Munch, K. & Schierup, M. H. (2014). Lineage sorting in apes. Annual Review of Genetics, 48, 519-535. https://doi.org/10.1146/annurev-genet-120213-092532

Hansen, S. K., Vestergaard, M., Thøgersen, L., Schiøtt, B., Nielsen, N. C. & Vosegaard, T. (2014). Lipid Dynamics Studied by Calculation of 31P Solid-State NMR Spectra Using Ensembles from Molecular Dynamics Simulations. Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 118(19), 5119-5129. https://doi.org/10.1021/jp5000304

Søndergaard, D., Knudsen, M. & Pedersen, C. N. S. (2014). Machine learning approaches to functional prediction of P-Type ATPases.

Hobolth, A. & Jensen, J. L. (2014). Markovian approximation to the finite loci coalescent with recombination along multiple sequences. Theoretical Population Biology, 98, 48-58. https://doi.org/10.1016/j.tpb.2014.01.002

Nordentoft, I. K., Lamy, P., Birkenkamp-Demtröder, K., Shumansky, K., Vang, S., Hornshøj, H., Juul, M., Villesen, P., Hedegaard, J., Roth, A., Thorsen, K., Høyer, S., Borre, M., Reinert, T., Fristrup, N., Dyrskjøt, L., Shah, S., Pedersen, J. S. & Ørntoft, T. F. (2014). Mutational context and diverse clonal development in early and late bladder cancer: Genomic changes in bladder cancer. Cell Reports, 7(5), 1649–1663. https://doi.org/10.1016/j.celrep.2014.04.038

Buttenschøn, H. N., Foldager, L., Elfving, B., Poulsen, P. H. P., Uher, R. & Mors, O. (2014). Neurotrophic factors in depression in response to treatment.

Hedegaard, J., Thorsen, K., Lund, M. K., Hein, A.-M. K., Hamilton-Dutoit, S. J., Vang, S., Nordentoft, I., Birkenkamp-Demtröder, K., Kruhøffer, M., Hager, H., Knudsen, B., Andersen, C. L., Sørensen, K. D., Pedersen, J. S., Orntoft, T. F. & Dyrskjøt, L. (2014). Next-generation sequencing of RNA and DNA isolated from paired fresh-frozen and formalin-fixed paraffin-embedded samples of human cancer and normal tissue. PLOS ONE, 9(5), e98187. https://doi.org/10.1371/journal.pone.0098187

Aagaard, J., Skadhede, S. C., Andersen, M. B., Kølbæk, P., Hastrup, L. H., Foldager, L. & Nielsen, J. A. (2014). Opsøgende Psykoseteams i Region Nordjylland: En monitoreringsundersøgelse med to års opfølgning af de Opsøgende Psykoseteams i Region Nordjylland og en registerbaseret undersøgelse af udviklingen i voksenpsykiatrien i Region Nordjylland. Aalborg Universitetsforlag.

Ehlers, B. & Bataillon, T. (2014). På forkant med selektionen. Evolution2. Weekendavisen.

Gusev, A., Lee, S. H., Trynka, G., Finucane, H., Vilhjálmsson, B. J., Xu, H., Zang, C., Ripke, S., Bulik-Sullivan, B., Stahl, E., Kähler, A. K., Hultman, C. M., Purcell, S. M., McCarroll, S. A., Daly, M., Pasaniuc, B., Sullivan, P. F., Neale, B. M., Wray, N. R. ... Schizophrenia Working Group of the Psychiatric Genomics Consortium (Manuel Mattheisen and Jakob Grove, members) (2014). Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases. American Journal of Human Genetics, 95(5), 535-52. https://doi.org/10.1016/j.ajhg.2014.10.004

Als, T. D., Lescai, F., Dahl, H. A., Grove, J., Demontis, D., Wang, A. G., Andorsdottir, G., Biskopstø, M., Johansen, O., Nyegaard, M., Bolund, L., Mors, O., Wang, J. & Børglum, A. (2014). Population Structure & Cryptic Relatedness of the isolated Population of the Faroe Islands. Poster session presented at XXII World Congress of Psychiatric Genetics, København, Denmark.

Blanquart, F., Achaz, G., Bataillon, T. & Tenaillon, O. (2014). Properties of selected mutations and genotypic landscapes under Fisher's geometric model. Evolution, 68(12), 3537-54. https://doi.org/10.1111/evo.12545

Dam, S., Dyrlund, T. F., Ussatjuk, A., Jochimsen, B., Nielsen, K., Goffard, N., Ventosa, M. A. L., Lorentzen, A. M., Gupta, V., Andersen, S. U., Enghild, J. J., Ronson, C. W., Roepstorff, P. & Stougaard, J. (2014). Proteome reference maps of the Lotus japonicus nodule and root. Proteomics, 14(2-3), 230-240. https://doi.org/10.1002/pmic.201300353

Perfeito, L., Sousa, A., Bataillon, T. & Gordo, I. (2014). Rates of fitness decline and rebound suggest pervasive epistasis. Evolution, 68(1), 150-162. https://doi.org/10.1111/evo.12234

Hobolth, A. & Jeff, T. (2014). Sampling and summary statistics of endpoint-conditioned paths in DNA sequence evolution. In M.-H. Chen, L. Kuo & P. O. Lewis (Eds.), Bayesian Phylogenetics: Methods, Algorithms, and Applications (1 ed., Vol. 1). CRC Press.

Sükösd, Z., Andersen, E. S. & Lyngsø, R. (2014). SCFGs in RNA secondary structure prediction: a hands-on approach. Methods in Molecular Biology, 1097, 143-62. https://doi.org/10.1007/978-1-62703-709-9__8, https://doi.org/10.1007/978-1-62703-709-9_8

Lindgreen, S., Krogh, A. & Pedersen, J. S. (2014). SNPest: a probabilistic graphical model for estimating genotypes. BMC Research Notes, 7, 698. https://doi.org/10.1186/1756-0500-7-698

Sanggaard, K. W., Bechsgaard, J. S., Fang, X., Duan, J., Dyrlund, T. F., Gupta, V., Jiang, X., Cheng, L., Fan, D., Feng, Y., Han, L., Huang, Z., Wu, Z., Liao, L., Settepani, V., Thøgersen, I. B., Vanthournout, B., Wang, T., Zhu, Y. ... Wang, J. (2014). Spider genomes provide insight into composition and evolution of venom and silk. Nature Communications, 5, Article 3765. https://doi.org/10.1038/ncomms4765

Nam, K., Munch, K., Hobolth, A., Y. Dutheil, J., Veeramah, K., Woerner, A., F. Hammer, M., Ape Genome Diversity Project, G., Mailund, T. & H. Schierup, M. (2014). Strong selective sweeps associated with ampliconic regions in great ape X chromosomes. arXiv.

Bay-Richter, C., Buttenschøn, H. N., Foldager, L., Kolstad, H. A., Kaerlev, L., Mors, O. & Wegener, G. (2014). Toxoplasma gondii seropositivity is positively associated with anxiety and burnout-syndrome. Abstract from CINP World Congress, Vancouver, Canada. https://doi.org/10.1017/S1461145714000741

Sand, A., Holt, M. K., Johansen, J., Brodal, G. S., Mailund, T. & Pedersen, C. N. S. (2014). tqDist: A Library for Computing the Quartet and Triplet Distances Between Binary and General Trees. Bioinformatics, 30(4), 2079-2080. https://doi.org/10.1093/bioinformatics/btu157

Munch, K., Schierup, M. H. & Mailund, T. (2014). Unraveling recombination rate evolution using ancestral recombination maps. BioEssays, 36(9), 892-900. https://doi.org/10.1002/bies.201400047

Aagaard, J., Nissen, F., Wernlund, A., Foldager, L. & Merinder, L. (2014). Valuable intervention against the excess mortality of psychiatric patients. Poster session presented at Annual Conference of the International Society for Bipolar Disorder, Seoul, Korea, Republic of. https://doi.org/10.1111/bdi.12189

Li, S., Besenbacher, S., Li, Y., Kristiansen, K., Grarup, N., Albrechtsen, A., Sparsø, T. H., Korneliussen, T. S., Hansen, T., Wang, J., Nielsen, R., Pedersen, O., Bolund, L. & Schierup, M. H. (2014). Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population. European Journal of Human Genetics. https://doi.org/10.1038/ejhg.2013.282

Jarvis, E. D., Mirarab, S., Aberer, A. J., Li, B., Houde, P., Li, C., Ho, S. Y. W., Faircloth, B. C., Nabholz, B., Howard, J. T., Suh, A., Weber, C. C., da Fonseca, R. R., Li, J., Zhang, F., Li, H., Zhou, L., Narula, N., Liu, L. ... Zhang, G. (2014). Whole-genome analyses resolve early branches in the tree of life of modern birds. Science, 346(6215), 1320-31. https://doi.org/10.1126/science.1253451

Thorgeirsson, T. E., Gudbjartsson, D. F., Sulem, P., Besenbacher, S., Styrkarsdottir, U., Thorleifsson, G., Walters, G. B., Furberg, H., Sullivan, P. F., Marchini, J., McCarthy, M. I., Steinthorsdottir, V., Thorsteinsdottir, U., Stefansson, K. & TAG Consortium (2013). A common biological basis of obesity and nicotine addiction. Translational Psychiatry, 3, e308. https://doi.org/10.1038/tp.2013.81

Sand, A., Holt, M. K., Johansen, J., Fagerberg, R., Pedersen, C. N. S., Brodal, G. S. & Mailund, T. (2013). Algorithms for Computing the Triplet and Quartet Distances for Binary and General Trees. Biology, 2(4), 1189-1209. https://doi.org/10.3390/biology2041189

Tataru, P., Sand, A., Hobolth, A., Mailund, T. & Pedersen, C. N. S. (2013). Algorithms for Hidden Markov Models Restricted to Occurrences of Regular Expressions. Biology, 2(4), 1282-1295. https://doi.org/10.3390/biology2041282

Abdallah, M., Larsen, N., Grove, J., Nørgaard-Pedersen, B., Thorsen, P., Mortensen, E. L. & Hougaard, D. M. (2013). Amniotic Fluid Inflammatory Cytokines: Potential Markers of Immunologic Dysfunction in Autism Spectrum Disorders. World Journal of Biological Psychiatry, 14(7), 528-538. https://doi.org/10.3109/15622975.2011.639803

Buttenschøn, H. N., Flint, T. J., Foldager, L., Qin, P., Christoffersen, S., Hansen, N. F., Kristensen, I. B., Mortensen, P. B., Børglum, A. D. & Mors, O. (2013). An association study of suicide and candidate genes in the serotonergic system. Journal of Affective Disorders, 148(2-3), 291-8. https://doi.org/10.1016/j.jad.2012.12.011

Sand, A., Pedersen, C. N. S., Mailund, T., Brodal, G. S. & Fagerberg, R. (2013). A practical O(n log² n) time algorithm for computing the triplet distance on binary trees. B M C Bioinformatics, 14(Suppl 2), S18. https://doi.org/10.1186/1471-2105-14-S2-S18

Hollegaard, M. V., Grauholm, J., Nielsen, R., Grove, J., Mandrup, S. & Hougaard, D. M. (2013). Archived neonatal dried blood spot samples can be used for accurate whole genome and exome-targeted next-generation sequencing. Molecular Genetics and Metabolism, 110(1-2), 65-72. https://doi.org/10.1016/j.ymgme.2013.06.004

Bataillon, T., Joyce, P. & Sniegowski, P. (2013). As it happens: current directions in experimental evolution. Biology Letters, 9(1), Article 20120945. https://doi.org/10.1098/rsbl.2012.0945

Sükösd, Z., Knudsen, B., Anderson, J. WJ., Novák, A., Kjems, J. & Pedersen, C. N. S. (2013). Characterising RNA secondary structure space using information entropy. B M C Bioinformatics, 14 (Suppl 2), 1-9. Article S22. https://doi.org/10.1186/1471-2105-14-S2-S22

Foldager, L., Als, T. D. & Grove, J. (2013). Comparison of methods for genome-wide gene-environment interaction analysis. Poster session presented at XXIst World Congress of Psychiatric Genetics, Boston, United States.

Siuda, I. & Thøgersen, L. (2013). Conformational flexibility of the leucine binding protein examined by protein domain coarse-grained molecular dynamics. Journal of Molecular Modeling, 19(11), 4931-4945. https://doi.org/10.1007/s00894-013-1991-9

Streja, E., Wu, C., Uldall, P. V., Grove, J., Arah, O. & Olsen, J. (2013). Congenital cerebral palsy, child sex and parent cardiovascular risk. PLOS ONE, 8(11), e79071. https://doi.org/10.1371/journal.pone.0079071

Buttenschøn, H. N., Elfving, B., Foldager, L., Plougmann, P. H., Andersen, J. H., Grynderup, M. B., Kærgaard, A., Hansen, Å. M., Kolstad, H. A., Kærlev, L., Bonde, J. P., Mikkelsen, S., Thomsen, J. F., Børglum, A., Wegener, G. & Mors, O. (2013). Depression and BMI influences the serum vascular endothelial growth factor level. Poster session presented at XXIst World Congress of Psychiatric Genetics, Boston, United States.

Brodal, G. S., Fagerberg, R., Mailund, T., Pedersen, C. N. S. & Sand, A. (2013). Efficient Algorithms for Computing the Triplet and Quartet Distance Between Trees of Arbitrary Degree. The Annual A C M - S I A M Symposium on Discrete Algorithms. Proceedings, 24, 1814-1832. http://knowledgecenter.siam.org/0236-000098/0236-000098/1

Nissen, K. K., Laska, M. J., Hansen, B., Terkelsen, T., Villesen, P., Bahrami, S., Petersen, T., Pedersen, F. S. & Nexø, B. A. (2013). Endogenous retroviruses and multiple sclerosis-new pieces to the puzzle. B M C Neurology, 13(111), 1-5. https://doi.org/10.1186/1471-2377-13-111

Sükösd, Z., Swenson, M. S., Kjems, J. & Heitsch, C. E. (2013). Evaluating the accuracy of SHAPE-directed RNA secondary structure predictions. Nucleic Acids Research, 41(5), 2807-2816. https://doi.org/10.1093/nar/gks1283

Castagnini, A., Foldager, L. & Bertelsen, A. (2013). Excess mortality of acute and transient psychotic disorders: comparison with bipolar affective disorder and schizophrenia. Acta Psychiatrica Scandinavica, 128(5), 370-375. https://doi.org/10.1111/acps.12077

Feldman, M. W., Christiansen, F. B. & Otto, S. P. (2013). Gene-culture co-evolution: teaching, learning, and correlations between relatives. Israel Journal of Ecology & Evolution, 59(2), 72-91. https://doi.org/10.1080/15659801.2013.853435

Simonsen, M., Christensen, M. H., Thomsen, R. & Pedersen, C. N. S. (2013). GPU-Accelerated High-Accuracy Molecular Docking using Guided Differential Evolution. In S. tsutsui & P. Collet (Eds.), Massively Parallel Evolutionary Computation on GPGPUs Springer Publishing Company.

Prado-Martinez, J., Sudmant, P. H., Kidd, J. M., Li, H., Kelley, J. L., Lorente-Galdos, B., Veeramah, K. R., Woerner, A. E., O'Connor, T. D., Santpere, G., Cagan, A., Theunert, C., Casals, F., Laayouni, H., Munch, K., Hobolth, A., Halager, A. E., Malig, M., Hernandez-Rodriguez, J. ... Marques-Bonet, T. (2013). Great ape genetic diversity and population history. Nature, 499, 471–475. https://doi.org/10.1038/nature12228

Radel, D., Sand, A. & Steel, M. (2013). Hide and seek: placing and finding an optimal tree for thousands of homoplasy-rich sequences. Molecular Phylogenetics and Evolution, 69(3), 1186–1189. https://doi.org/10.1016/j.ympev.2013.08.001

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Palle Villesen