Publications

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Simonsen, M. (2011). Efficient algorithms for tree reconstruction and prediction of molecular interactions. Department of Computer Science, Aarhus University.

Nielsen, J. (2011). Engineering Algorithms for Finding Patterns in Biological Data.

Furrow, R., Christiansen, F. & Feldman, M. (2011). Environment-sensitive Epigenetics and the Heritability of Complex Diseases. Genetics, 189(4), 1377-1387. https://doi.org/10.1534/genetics.111.131912

Mailund, T., Dutheil, J., Hobolth, A., Lunter, G. & Schierup, M. H. (2011). Estimating Divergence Time and Ancestral Effective Population Size of Bornean and Sumatran Orangutan Subspecies Using a Coalescent Hidden Markov Model. P L o S Genetics, 7(3). https://doi.org/10.1371/journal.pgen.1001319

Rafnar, T., Vermeulen, S. H., Sulem, P., Thorleifsson, G., Aben, K. K., Witjes, J. A., Grotenhuis, A. J., Verhaegh, G. W., Hulsbergen-van de Kaa, C. A., Besenbacher, S., Gudbjartsson, D., Stacey, S. N., Gudmundsson, J., Johannsdottir, H., Bjarnason, H., Zanon, C., Helgadottir, H., Jonasson, J. G., Tryggvadottir, L. ... Kiemeney, L. A. (2011). European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene. Human Molecular Genetics, 20(21), 4268-4281. https://doi.org/10.1093/hmg/ddr303

Maetschke, S. R., Simonsen, M., Davis, M. J. & Mark, A. (2011). Gene Ontology-driven inference of protein-protein interactions using inducers. Bioinformatics, 28(1), 69-75. https://doi.org/10.1093/bioinformatics/btr610

Li, Q., Li, N., Hu, X., Li, J., Du, Z., Chen, L., Yin, G., Duan, J., Zhang, H., Zhao, Y., Wang, J. & Li, N. (2011). Genome-wide mapping of DNA methylation in chicken. P L o S One, 6(5), e19428. https://doi.org/10.1371/journal.pone.0019428

Grove, J., Demontis, D., Hollegaard, M. V., Pedersen, C. B., Ørntoft, T. F., Yolken, R., Didriksen, M., Hougaard, D., Wiuf, C. H., Mors, O., Mortensen, P. B. & Børglum, A. (2011). Genome-Wide Significant Interaction by Cytomegalovirus with Respect to Risk of Schizophrenia. Poster session præsenteret på XIX World Congress on Psychiatric Genetics, Washington DC, USA.

Slotte, T., Bataillon, T., Hansen, T. T., St Onge, K., Wright, S. I. & Schierup, M. H. (2011). Genomic determinants of protein evolution and polymorphism in Arabidopsis. Genome Biology and Evolution, 3, 1210-1219. https://doi.org/10.1093/gbe/evr094

Simonsen, M., Thomsen, R., Christensen, M. H. & Pedersen, C. N. S. (2011). GPU-Accelerated High-Accuracy Molecular Docking using Guided Differential Evolution. I GECCO'11 Proceedings of the 13th annual conference on Genetic and evolutionary computation (s. 1803-1810). Association for Computing Machinery. https://doi.org/10.1145/2001576.2001818

Luo, Y., Li, J., Liu, Y., Lin, L., Du, Y., Li, S., Yang, H., Vajta, G., Callesen, H., Bolund, L. & Sørensen, C. B. (2011). High efficiency of BRCA1 knockout using rAAV-mediated gene targeting: developing a pig model for breast cancer. Transgenic Research, 20, 975-988. https://doi.org/10.1007/s11248-010-9472-8

Wiechec, E., Wiuf, C., Overgaard, J. & Hansen, L. L. (2011). High-resolution melting analysis for mutation screening of RGSL1, RGS16, and RGS8 in breast cancer. Cancer Epidemiology, Biomarkers & Prevention, 20(2), 397-407. https://doi.org/10.1158/1055-9965.EPI-10-0514

Jensen, T. D., Li, J., Wang, K., Lindebjerg, J., Kølvraa, S., Bolund, L., Jakobsen, A., Bruun-Petersen, G., Li, S. & Crüger, D. G. (2011). Identification of chromosome aberrations in sporadic microsatellite stable and unstable colorectal cancers using array comparative genomic hybridization. Cancer Genetics and Cytogenetics, 204(2), 84-95. https://doi.org/10.1016/j.cancergencyto.2010.08.019

Martins, H. & Villesen, P. (2011). Improved integration time estimation of endogenous retroviruses with phylogenetic data. P L o S One, 6(3), e14745. https://doi.org/10.1371/journal.pone.0014745

Hobolth, A., Dutheil, J., Hawks, J., Schierup, M. H. & Mailund, T. (2011). Incomplete lineage sorting patterns among human, chimpanzee and orangutan suggest recent orangutan speciation and widespread selection. Genome Research, 21(3), 349-356. https://doi.org/10.1101/gr.114751.110

Simonsen, M., Mailund, T. & Pedersen, C. N. S. (2011). Inference of Large Phylogenies Using Neighbour-Joining. Biomedical Engineering Systems and Technologies, 127(5), 334-344. https://doi.org/10.1007/978-3-642-18472-7_26

Andersen, L. N. (2011). Inferring Population Histories In The IM-model Using Site Pattern Analysis. Poster session præsenteret på SMBE 2011, Kyoto, Japan.

Villesen, P., Gosmer, K. & Lindholst, C. (2011). Kemiske fingeraftryk fælder narkoforbryderne. Aktuel Naturvidenskab, (3).

Bache, C., Christiansen, F., Harder, P., Rørdam, M., Smith, N. & Sneppen, K. (2011). Kvalitet i universitetsuddannelserne - forskningsbaseret undervisning: Forskningspolitisk årsmøde 2011. Det Kongelige Danske Videnskabernes Selskab.

Sahana, G., Mailund, T., Lund, M. S. & Guldbrandtsen, B. (2011). Local Genealogies in a Linear Mixed Model for Genome-wide Association Mapping in Complex Pedigreed Populations. P L o S One, 6(11).

Andersen, L. N. & Asmussen, S. (2011). Local time asymptotics for centered Lévy processes with two-sided reflection. Stochastic Models, 27(2), 202-219. https://doi.org/10.1080/15326349.2011.567928

Gregersen, N., Buttenschøn, H. N., Dahl, HA., Foldager, L., Kristensen, A. S., Woldbye, D. P. D., Kofoed, P., Joensen, S., Kruse, T. A., Wang, A. G., Børglum, A. & Mors, O. (2011). Markers on chromosome 19p13 are associated with panic disorder. Poster session præsenteret på PhD Day 2011, Aarhus University, Faculty of Health Sciences, Aarhus, Danmark.

Asmussen, S. & Hobolth, A. (2011). Markov bridges, bisection and variance reduction. Thiele Centre, Institut for Matematiske Fag, Aarhus Universitet.

Knudsen, M., Feliu, E. & Wiuf, C. H. (2011). Mathematical Modeling of Phosphorelay Dynamics. Poster session præsenteret på The XII International Congress on Molecular Systems Biology, Lleida, Spanien.

De Mita, S., Chantret, N., Loridon, K., Ronfort, J. & Bataillon, T. (2011). Molecular adaptation in flowering and symbiotic recognition pathways: insights from patterns of polymorphism in the legume Medicago truncatula. B M C Evolutionary Biology, 11(1), 229-241. https://doi.org/10.1186/1471-2148-11-229

Lie, M. A., Thomsen, R., Pedersen, C. N. S., Schiøtt, B. & Christensen, M. H. (2011). Molecular Docking with Ligand Attached Water Molecules. Journal of Chemical Information and Modeling, 51(4), 909-917. https://doi.org/10.1021/ci100510m

Grivet, D., Sebastiani, F., Alía, R., Bataillon, T., Torre, S., Zabal-Aguirre, M., Vendramin, G. G. & González-Martínez, S. C. (2011). Molecular footprints of local adaptation in two Mediterranean conifers. Molecular Biology and Evolution, 28(1), 101-16. https://doi.org/10.1093/molbev/msq190

Rafnar, T., Gudbjartsson, D. F., Sulem, P., Jonasdottir, A., Sigurdsson, A., Jonasdottir, A., Besenbacher, S., Lundin, P., Stacey, S. N., Gudmundsson, J., Magnusson, O. T., le Roux, L., Orlygsdottir, G., Helgadottir, H. T., Johannsdottir, H., Gylfason, A., Tryggvadottir, L., Jonasson, J. G., de Juan, A. ... Stefansson, K. (2011). Mutations in BRIP1 confer high risk of ovarian cancer. Nature Genetics, 43(11), 1104-7. https://doi.org/10.1038/ng.955

Sonntag, Y., Musgaard, M., Olesen, C., Schiøtt, B., Møller, J. V., Nissen, P. & Thøgersen, L. (2011). Mutual adaptation of a membrane protein and its lipid bilayer during conformational changes. Nature Communications, 2, 304. https://doi.org/10.1038/ncomms1307

Hobolth, A., Andersen, L. N. & Mailund, T. (2011). On computing the coalescence time density in an isolation-with-migration model with few samples. Genetics, 187, 1242-1243. https://doi.org/10.1534/genetics.110.124164

Larsen, J. K., Foldager, L., Bendsen, B. B. & Munk-Jørgensen, P. (2011). Prematurity and low birth weight as risk factors for the development of affective disorder, especially depression and schizophrenia: a register study. Poster session præsenteret på American Psychiatric Association 164th Annual Meeting, Honolulu, Hawaii, USA.

Musgaard, M., Thøgersen, L. & Schiøtt, B. (2011). Protonation States of Important Acidic Residues in the Central Ca²⁺ Ion Binding Sites of the Ca²⁺-ATPase: A Molecular Modeling Study. Biochemistry, 50(51), 11109-11120. https://doi.org/10.1021/bi201164b

Abdallah, M., Greaves-Lord, K., Grove, J., Nørgaard-Pedersen, B., Hougaard, D. M. & Mortensen, E. L. (2011). Psychiatric Comorbidities in Autism Spectrum Disorders: Findings from a Danish Historic Birth Cohort. European Child & Adolescent Psychiatry, 20(11-12), 599-601. https://doi.org/10.1007/s00787-011-0220-2

Simonsen, M. & Pedersen, C. N. S. (2011). Rapid Computation of Distance Estimators from Nucleotide and Amino Acid Alignments. I Proceedings of the 26th Annual ACM Symposium on Applied Computing Association for Computing Machinery.

Østergaard, S. D. & Foldager, L. (2011). Reply. Acta Psychiatrica Scandinavica, 124(1), 75-6. https://doi.org/10.1111/j.1600-0447.2011.01694.x

Hvidtjørn, D., Grove, J., Schendel, D., Schieve, L., Sværke, C., Ernst, E. & Thorsen, P. (2011). Risk of Autism Spectrum Disorders in children born after assisted conception. A population based follow-up study. Journal of Epidemiology & Community Health, 65(6), 497-502. https://doi.org/10.1136/jech.2009.093823

Hollegaard, M. V., Grove, J., Grauholm, J., Kreiner-Moller, E., Bonnelykke, K., Nørgaard, M., Benfield, T. L., Norgaard-Pedersen, B., Mortensen, P. B., Mors, O., Sørensen, H. T., Harboe, Z. B., Børglum, A., Demontis, D., Ørntoft, T. F., Bisgaard, H. & Hougaard, D. M. (2011). Robustness of genome-wide scanning using archived dried blood spot samples as a DNA source. B M C Genetics, 12(1), 58. https://doi.org/10.1186/1471-2156-12-58

Østergaard, S. D., Dinesen, P. T. & Foldager, L. (2011). Sensitivity x PPV is a recognized test called the clinical utility index (CUI+). The Authors Reply. European Journal of Epidemiology, 26, 252-252. https://doi.org/10.1007/s10654-011-9561-x

Lorenzen, E. D., Nogués-Bravo, D., Orlando, L., Weinstock, J., Binladen, J., Marske, K. A., Ugan, A., Borregaard, M. K., Gilbert, M. T. P., Nielsen, R., Ho, S. Y. W., Goebel, T., Graf, K. E., Byers, D., Stenderup, J., Rasmussen, M., Campos, P., Leonard, J. A., Koepfli, K.-P. ... Willerslev, E. (2011). Species-specific responses of Late Quaternary megafauna to climate and humans. Nature, 479(7373), 359-64. https://doi.org/10.1038/nature10574

Andersen, L. N. (2011). Subexponential loss rate asymptotics for Lévy processes. Mathematical Methods of Operations Research, 73(1), 91-108. https://doi.org/10.1007/s00186-010-0335-0

Hobolth, A. & Jensen, J. L. (2011). Summary statistics for endpoint-conditioned continuous-time Markov chains. Journal of Applied Probability, 48(4), 911-924. https://doi.org/10.1239/jap/1324046009

Balslev, H., Arge, L. A., Svenning, J.-C., Schierup, M. H. & Jensen, C. S. (red.) (2011). Symposium on Biodiversity in the Silicon Age - Abstracts. The Royal Danish Academy of Sciences and Letters.

Østergaard, S. D. & Foldager, L. (2011). The association between physical illness and major depressive episode in general practice. Acta Psychiatrica Scandinavica, 123(4), 290-296. https://doi.org/10.1111/j.1600-0447.2010.01668.x

Stukenbrock, E. H., Bataillon, T., Dutheil, J. Y., Hansen, T. T., Li, R., Zala, M., McDonald, B. A., Wang, J. & Schierup, M. H. (2011). The making of a new pathogen: Insights from comparative population genomics of the domesticated wheat pathogen Mycosphaerella graminicola and its wild sister species. Genome Research, 21, 2157-2166. https://doi.org/10.1101/gr.118851.110

Kristensen, T. G., Nielsen, J. & Pedersen, C. N. S. (2011). Using Inverted Indices for Accelerating LINGO Calculations. Journal of Chemical Information and Modeling, 51(3), 597-600. https://doi.org/10.1021/ci100437e

Andersen, F. F., Villesen, P., Knudsen, B., Wiuf, C. H., Desideri, A. & Knudsen, B. R. (2011). Utilization of Computer Science for Construction and Characterization of DNA nano-Structures. I DNA Microarrays, Synthesis and Synthetic DNA Nova Science Publishers.

Kristensen, T. G. (2011). Virtual screening algorithms. Department of Computer Science, Aarhus University.

Branca, A., Paape, T. D., Zhou, P., Briskine, R., Farmer, A. D., Mudge, J., Bharti, A. K., Woodward, J. E., May, G. D., Gentzbittel, L., Ben, C., Denny, R., Sadowsky, M. J., Ronfort, J., Bataillon, T., Young, N. D. & Tiffin, P. (2011). Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula. Proceedings of the National Academy of Sciences (PNAS), 108(42), 864-870. https://doi.org/10.1073/pnas.1104032108

Nielsen, J., le Quach, P., Emborg, C., Foldager, L. & Correll, C. U. (2010). 10-Year trends in the treatment and outcomes of patients with first-episode schizophrenia. Acta Psychiatrica Scandinavica, 122(5), 356-66. https://doi.org/10.1111/j.1600-0447.2010.01576.x

Mai, D. M., Sahana, G., Christiansen, F. & Guldbrandtsen, B. (2010). A genome-wide association study for milk production traits in Danish Jersey cattle using a 50K single nucleotide polymorphism chip. Journal of Animal Science, 88, 3522-3528.

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