Danish pan genome paper pronounced most significant Danish research 2017 by videnskab.dk

2018.01.05 | Ellen Bernadette Noer

cover suggestion for Nature article (Illustration: Astrid Reitzel)

The readers of videnskab.dk have voted the Danish pan genome study to be the most significant Danish research result in 2017. The main project, published in Nature July 2017 (https://www.nature.com/articles/nature23264), is a major Danish collaboration where researchers from BiRC played a very central part. The assembly and analysis of the 150 genomes of Danish descent made extensive use of the supercomputers GenomeDK at Aarhus University and Computerome at Copenhagen University/DTU. The Danish pan genome will be an important basis for future Danish ventures into personalised medicine. It also allowed a better resolution of variation in the important MHC system (a cluster of immune system genes) published alongside the main paper in Genome Research 
(http://genome.cshlp.org/content/early/2017/08/03/gr.218891.116) and at the Y chromosome in PLOS Genetics (http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006834)

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