BiRC's task force is aimed at helping university researchers in need of bioinformatics consultant help. Examples of work/help include:

• automated blasting against whole genomes or custom libraries and customized blast output/analysis
• automated data formatting, selection and filtering
• visualization of results
• simple statistical analysis of data
• computational analysis of data

Whether we can take on a task depends on the job to be done, availability of consultants and how time consuming the job appears to be. Some tasks develop into small collaborative projects. If you have a task and would like to use the task force, you should email us:

Carsten Wiuf (wiuf@birc.au.dk) or Palle Villesen Fredsted (palle@birc.au.dk)

• BLAST mapping of viral integration sites in the mouse genome
• Identification of gene regions with changed expression in leukaemia
• Correlation analysis of disease and genotype status in colon cancer
• Association mapping in cervix tumours
• Identification of unique probing regions in various DNA databases
• Identification of up- and down regulated genes in cell lines with varying oxygen supply
• miRNA target identification and selection

• Staunstrup NH, Moldt B, Mátés L, Villesen P, Jakobsen M, Ivics Z, Izsvák Z, Mikkelsen JG. 2009 Hybrid Lentivirus-transposon Vectors With a Random Integration Profile in Human Cells. Molecular Therapy (2009); doi:10.1038/mt.2009.10
• Christensen LL, Madsen BE, Wikman FP, Wiuf C, Koed K, Tjonneland A, Olsen A, Syvanen A-C, Andersen CL, Orntoft TF. 2008 The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population. BMC Med Genet 9: 52.
• Madsen BE, Ramos EM, Boulard M, Duda, Overgaard J, Nordsmark M, Wiuf C, Hansen LL. 2008 Germline mutation in RNASEL predicts increased risk of head and neck, uterine cervix and breast cancer. PLoS One 3: e2492.